IL-31 for Canine Atopic Dermatitis

Zoetis has been granted conditional release of their Canine Atopic Dermatitis Immunotherapeutic monoclonal antibody against IL-31. This injection has been developed for managing pruritus in dogs by binding their IL-31 with a monoclonal antibody. Like Apoquel (oclacitinib), it has the potential to reduce pruritus within 24 to 48 hours with a single subcutaneous injection lasting up to 3 to 6 weeks depending on the dose and responsiveness of the patient. Approximately 90% of patients respond…

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New Topical Therapy for Feline Eosinophilic Keratoconjunctivitis

Feline eosinophilic keratoconjunctivitis is an inflammatory condition that affects the cornea and/or conjunctiva.  It is characterized by mucopurulent discharge and pink/white raised plaques on the cornea or conjunctiva.  Eosinophils are often noted on corneal cytology which confirms the diagnosis. Treatment of eosinophilic keratoconjunctivitis Treatment of eosinophilic keratoconjunctivitis is topical anti-inflammatory therapy with either cyclosporine, tacrolimus, or prednisolone acetate combined with a topical antiviral or oral therapy with megestrol acetate.  Side effects of topical therapy include…

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Treatment Update for Keratoconjunctivitis Sicca in Dogs

Keratoconjunctivitis sicca (KCS) is a common eye disease in dogs.  The prevalence of KCS in the dog ranges from 1 to 4%.  KCS in dogs can cause ocular discharge, pain, corneal scarring and ulceration. In fact, one of the most common causes of a corneal ulcer in the dog is KCS. Diagnosing a dog with KCS is based on low Schirmer tear testing (<15mm/min) as well as other ocular symptoms blepharospasm, mucoid to mucopurulent discharge,…

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