Current Clinical Studies

Dogs With Lens Changes

At MedVet Columbus

Overview:

MedVet Columbus is enrolling dogs with Nuclear sclerosis or cataracts in a study to evaluate the safety and efficacy of a topical ophthalmic solution in delaying the progression and/or reversal of lens changes in dogs. Patients will be randomized into one of two dose concentration groups.

Qualifications to Enroll:

• Dogs must be diagnosed with bilateral nuclear sclerosis or cataracts (with or without diabetes) by the Primary Investigator
• Dogs must not have KCS, glaucoma, uveitis, or lens luxation
• Patients may not have been part of another clinical trial in the past 6 months
• Dogs must not have any active infections or systemic organ dysfunction that would limit full participation in the study
• Owners must be able to return for all study visits (screening, week 2, week 4, week 8, week 16)
• Owners must be able to treat their dog with eye drops three times a day.

Client Savings:

All costs associated with the study will be covered by the study sponsor including: ocular exams by a board certified ophthalmologist, photographs, labwork, and test article. Owners that complete the full study will be eligible for a sponsor incentive (Prepaid gift card) as well as the possibility of continued use of the product and additional exams up to one year.

Contact:

Columbus: Dr. Terah Webb at terah.webb@medvet.com or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvet.com or 614-310-1720

Cancer Diagnostic Study for Dogs with Suspected Hemangiosarcoma or Mammary Carcinoma

At MedVet Columbus and MedVet Indianapolis

Overview:

MedVet is currently enrolling dogs in a multi-center research study investigating the feasibility of a new cancer diagnostic test. Sponsor is requesting one peripheral blood sample prior to tumor removal. Owners must allow the biopsy results to be shared with the sponsor. Patients will be evaluated by the appropriate specialty department to confirm eligibility.

Criteria:

Patients must meet the following criteria:

• Dogs must display clinical signs of Hemangiosarcoma or Mammary Carcinoma (excluding spayed females for suspected mammary carcinoma cases)
• Patients must be tumor bearing
• Not currently being treated for cancer
• Planning or willing to have tumor section removed for histopathology analysis

Client Savings:

The sponsor will pay $200 towards the owner’s invoice for tumor biopsy or removal.

Primary Study Contacts:

Columbus Location:

Edna Moore (Clinical Studies Coordinator) at edna.moore@medvetforpets.com or 614.310.1720

Indianapolis location:

Dr. Mike Lucroy (Medical Oncology and Director of Clinical Studies) at Michael.lucroy@medvetforpets.com or 317.872.8387.

Dogs in Need of an Amputation

AT MEDVET COLUMBUS

Overview:

MedVet Columbus is currently enrolling patients in a clinical study to evaluate the outcomes associated with two different methods of wound closure after limb amputation. Each patient will be examined by a veterinary surgeon to determine if he/she is an appropriate candidate for amputation. If your dog is eligible, at the time of surgery he/she will be randomly assigned to have the surgical site closed with or without placement of a closed suction drain. The drain will remain in place for approximately one week. A closed suction drain requires emptying at home two to three times a day until it is removed.

All owners must be willing and able to present patients for follow-up examinations at one, two, and four weeks postoperatively. Owners will be asked to evaluate their dog’s overall pain, level of pain interference, and overall quality of life and veterinarians will assess comfort, ambulation, incisional healing and any other complications.

Qualifications to Enroll:

• Patients will be evaluated by a member of the surgery service to confirm eligibility
• Dogs must be greater than 26.4 pounds (12 kilograms)
• Either forelimb or hind limb amputations
• Reason for amputation may include cancer, trauma, peripheral nerve problems, or severe infections
• Dogs are excluded if the patient requires an additional surgical procedure (e.g. eyelid mass removal)

Client Savings:

Clients will have three free follow-up examinations courtesy of the surgery department at 1, 2, and 4 weeks post-amputation.

Primary Study Contacts

Columbus location:

Dr. Megan Mathews (Surgery) at mmathews@medvet.com, Dr. Jennifer Carr (Surgery) at Jennifer.carr@medvet.com, or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvet.com

Past Clinical Trials at MedVet Hospitals

The following trials are no longer accepting new patients:

• Dogs With Protein Losing Enteropathy
• Dogs with Dry Eye
• Dogs With Osteosarcoma
• Large Dogs Requiring Ruptured Cranial Cruciate Ligament Repair
• Cats with Diabetes Mellitus
• Small dogs requiring ruptured cranial cruciate ligament repair
• Dogs with pruritus
• Dogs with osteoarthritis
• Large dogs requiring ruptured cranial cruciate ligament repair
• Dogs with congestive heart failure (4 completed studies)
• Dogs with t-cell lymphoma
• Dogs with congestive heart failure (multi site study)
• Dogs with mast cell tumors
• Dogs with diabetes mellitus (2 completed studies)
• Dogs with hip dysplasia
• Dogs requiring cranial cruciate or luxating patella repair surgery (post-operative pain study)
• Dogs with ruptured cranial cruciate ligaments
• Dogs with melanoma, osteosarcoma, soft tissue sarcoma, and squamous cell carcinoma
• Cats with congestive heart failure
• Dogs with nasal carcinoma
• Cats with oral squamous cell carcinoma
• Dogs with atopic disease
• Dogs with epilepsy
• Dogs with lymphoma
• Dogs with Glioma

Contact Us

If you have a pet that you believe may qualify for a clinical study, please contact your primary care veterinarian and they can work with us to determine if a clinical trial is the best option for your pet. If you are a veterinarian with a patient that you believe could benefit from a clinical study, please contact us.

MedVet Clinical Trials

(614) 310-1722

clinical.studies@medvetforpets.com

If you would like to learn more about MedVet’s Clinical Studies Center or how you can collaborate with one of the clinical investigative teams at MedVet, click here.