Current Clinical Studies

Cats with Feline Chronic Gingivostomatitis

MedVet Indianapolis

Overview:

MedVet Indianapolis is currently enrolling cats with chronic gingivostomatitis that have not responded to standard treatment in a study to evaluate the safety and efficacy of a stem cell based therapy to treat cats with FCGS that have not had success with other treatments. This is a multi-site study based on research completed at UC Davis.

Qualifications to Enroll:

• Cats must at least one year old and greater than or equal to 2kgs.
• Cats must have documented diagnosis of FCGS and have undergone full standard of care therapy, full or pre-molar tooth extractions but are non-responsive for at least three to six months following extractions despite ongoing medical therapy.
• Cats with co-morbidities are allowed as long as they will not interfere with treatment or evaluation of efficacy of the test article.
• Owners must be able to return for all study visits over a 12-month period.
• Cats may not have any planned surgical procedures for the duration of the study.
• Cats must be free of anti-inflammatory and immunosuppressant therapy for 28 days prior to therapy and remain off those therapies during the trial. Cats can be on these therapies at the time of the first examination with the MedVet BOARD CERTIFIED VETERINARY DENTIST™.

Client Savings:

Labwork and the stem cell therapy will be provided to the owner at no charge.  The owner is responsible for the office call and costs associated with the administration of the stem cell therapy.

Contact:

Indianapolis:

Edna Moore (Clinical Studies Coordinator) at edna.moore@medvet.com or 614.310.1720

Dogs in Need of an Amputation

At MedVet Columbus

Overview:

MedVet Columbus is currently enrolling patients in a clinical study to evaluate the outcomes associated with two different methods of wound closure after limb amputation. Each patient will be examined by a veterinary surgeon to determine if he/she is an appropriate candidate for amputation. If your dog is eligible, at the time of surgery he/she will be randomly assigned to have the surgical site closed with or without placement of a closed suction drain. The drain will remain in place for approximately one week. A closed suction drain requires emptying at home two to three times a day until it is removed.

All owners must be willing and able to present patients for follow-up examinations at one, two, and four weeks postoperatively. Owners will be asked to evaluate their dog’s overall pain, level of pain interference, and overall quality of life and veterinarians will assess comfort, ambulation, incisional healing and any other complications.

Qualifications to Enroll:

• Patients will be evaluated by a member of the surgery service to confirm eligibility
• Dogs must be greater than 26.4 pounds (12 kilograms)
• Either forelimb or hind limb amputations
• Reason for amputation may include cancer, trauma, peripheral nerve problems, or severe infections
• Dogs are excluded if the patient requires an additional surgical procedure (e.g. eyelid mass removal)

Client Savings:

Clients will have three free follow-up examinations courtesy of the surgery department at 1, 2, and 4 weeks post-amputation.

Contact:

Columbus:

Dr. Megan Mathews (Surgery) at mmathews@medvet.com, Dr. Jennifer Carr (Surgery) at Jennifer.carr@medvet.com, or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvet.com

Past Clinical Trials at MedVet Hospitals

The following trials are no longer accepting new patients:

• Dogs With Protein Losing Enteropathy
• Dogs with Dry Eye
• Dogs With Osteosarcoma
• Large Dogs Requiring Ruptured Cranial Cruciate Ligament Repair
• Cats with Diabetes Mellitus
• Small dogs requiring ruptured cranial cruciate ligament repair
• Dogs with pruritus
• Dogs with osteoarthritis
• Large dogs requiring ruptured cranial cruciate ligament repair
• Dogs with congestive heart failure (4 completed studies)
• Dogs with t-cell lymphoma
• Dogs with congestive heart failure (multi-site study)
• Dogs with mast cell tumors
• Dogs with diabetes mellitus (2 completed studies)
• Dogs with hip dysplasia
• Dogs requiring cranial cruciate or luxating patella repair surgery (post-operative pain study)
• Dogs with ruptured cranial cruciate ligaments
• Dogs with melanoma, osteosarcoma, soft tissue sarcoma, and squamous cell carcinoma
• Cats with congestive heart failure
• Dogs with nasal carcinoma
• Cats with oral squamous cell carcinoma
• Dogs with atopic disease
• Dogs with epilepsy
• Dogs with lymphoma
• Dogs with Glioma
• Dogs With Lens Changes

Contact Us

If you have a pet that you believe may qualify for a clinical study, please contact your primary care veterinarian and they can work with us to determine if a clinical trial is the best option for your pet. If you are a veterinarian with a patient that you believe could benefit from a clinical study, please contact us.

MedVet Clinical Trials

(614) 310-1722

clinical.studies@medvetforpets.com

If you would like to learn more about MedVet’s Clinical Studies Center or how you can collaborate with one of the clinical investigative teams at MedVet, click here.