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Current Clinical Studies

MedVet Clinical Studies Current Clinical Studies

Cancer Diagnostic Study for Dogs with Suspected Hemangiosarcoma or Mammary Carcinoma

At MedVet Columbus and MedVet Indianapolis

Overview:

MedVet is currently enrolling dogs in a multi-center research study investigating the feasibility of a new cancer diagnostic test. Sponsor is requesting one peripheral blood sample prior to tumor removal. Owners must allow the biopsy results to be shared with the sponsor. Patients will be evaluated by the appropriate specialty department to confirm eligibility.

Criteria:

Patients must meet the following criteria:

  • Dogs must display clinical signs of Hemangiosarcoma or Mammary Carcinoma (excluding spayed females for suspected mammary carcinoma cases)
  • Patients must be tumor bearing
  • Not currently being treated for cancer
  • Planning or willing to have tumor section removed for histopathology analysis

Client Savings:

The sponsor will pay $200 towards the owner’s invoice for tumor biopsy or removal.

Primary Study Contacts:

Columbus Location:

Edna Moore (Clinical Studies Coordinator) at edna.moore@medvetforpets.com or 614.310.1720

Indianapolis location:

Dr. Mike Lucroy (Medical Oncology and Director of Clinical Studies) at Michael.lucroy@medvetforpets.com or 317.872.8387.

Dogs With Osteosarcoma

At MedVet Columbus and MedVet Indianapolis

MedVet Columbus and MedVet Indianapolis are currently enrolling patients with osteosarcoma who have undergone amputation and chemotherapy in a study of the Canine Osteosarcoma Vaccine, Live Listeria Vector (COV-LLV), a conditionally licensed product.  We will confirm eligibility by reviewing your dog’s medical history, performing a physical exam, taking thoracic radiographs, and submitting routine blood and urine testing.  All dogs enrolled in the study will be treated with the vaccine.

Qualifications to Enroll:

• Patients must have a histopathologic or cytologic diagnosis of osteosarcoma
• Amputation of the affected limb followed by a completed chemotherapy regimen (carboplatin and/or doxorubicin).  This may be completed at MedVet or another hospital as long as accurate records are provided
• Have no clinically relevant abnormalities on labwork or any uncontrolled medical condition that may be disruptive to the study
• Have no evidence of pulmonary metastases
• Patients may not have be treated with prior immunotherapeutic treatment for osteosarcoma

Client Savings:

Blood and urine testing will be covered by the study sponsor.  The sponsor will also cover medication for side effects (up to $350).

Contact:

Columbus location:  Dr. Lisa Fulton  (Medical Oncology) at 614.431.4401 or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvetforpets.com or 614.310.1720.

Indianapolis Location:  Dr. Michael Lucroy (Medical Oncology) at 317.872.8387 or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvetforpets.com or 614.310.1720.

Dogs With Protein Losing Enteropathy

AT MEDVET COLUMBUS

Overview:

MedVet Columbus is currently enrolling patients in a study investigating low fat and ultra-low fat diets as a primary treatment approach for dogs with evidence of protein losing enteropathy, in lieu of traditional treatment with immunosuppressive corticosteroids. Eligibility will be confirmed with blood work, urinalysis, abdominal ultrasound and/or gastrointestinal biopsy, and physical examination findings. The study duration is six months and includes 4 re-check exams.

Qualifications to Enroll:

  • Patients must have a histologic or ultrasonographic diagnosis of abnormal small intestinal lacteal dilation (lymphangiectasia)
  • Bloodwork and urinalysis results compatible with a diagnosis of protein losing enteropathy
  • Have no complicating concurrent medical condition that might be disruptive to the study
  • Have not received systemic corticosteroid treatment in the last 30 days before entering the study

Client Savings:

Once enrollment criteria are satisfied, all subsequent consultation fees with the Internal Medicine Service will be at no charge for the duration of the study. The final re-check bloodwork and limited ultrasound exam will also be performed at no charge. The client will be responsible for bloodwork fees for the first 3 recheck exams.

Contact:

Dr. Marc Myers (Internal Medicine) at 614.431.4428

Dogs in Need of an Amputation

AT MEDVET COLUMBUS

Overview:

MedVet Columbus is currently enrolling patients in a clinical study to evaluate the outcomes associated with two different methods of wound closure after limb amputation. Each patient will be examined by a veterinary surgeon to determine if he/she is an appropriate candidate for amputation. If your dog is eligible, at the time of surgery he/she will be randomly assigned to have the surgical site closed with or without placement of a closed suction drain. The drain will remain in place for approximately one week. A closed suction drain requires emptying at home two to three times a day until it is removed.

All owners must be willing and able to present patients for follow-up examinations at one, two, and four weeks postoperatively. Owners will be asked to evaluate their dog’s overall pain, level of pain interference, and overall quality of life and veterinarians will assess comfort, ambulation, incisional healing and any other complications.

Qualifications to Enroll:

  • Patients will be evaluated by a member of the surgery service to confirm eligibility
  • Dogs must be greater than 26.4 pounds (12 kilograms)
  • Either forelimb or hind limb amputations
  • Reason for amputation may include cancer, trauma, peripheral nerve problems, or severe infections
  • Dogs are excluded if the patient requires an additional surgical procedure (e.g. eyelid mass removal)

Client Savings:

Clients will have three free follow-up examinations courtesy of the surgery department at 1, 2, and 4 weeks post-amputation.

Primary Study Contacts

Columbus location:

Dr. Megan Mathews (Surgery) at mmathews@medvet.com, Dr. Jennifer Carr (Surgery) at Jennifer.carr@medvet.com, or Edna Moore (Clinical Studies Coordinator) at edna.moore@medvet.com

Cancer Therapy Study For Dogs With Newly Diagnosed Untreated Lymphoma

At MedVet Indianapolis

Overview:

MedVet is currently enrolling dogs in a clinical study investigating a new, highly-targeted, non-chemotherapy treatment for multicentric lymphoma. The medical oncology team will evaluate dogs to confirm eligibility. Owners must be willing and able to return to MedVet for up to 6 weekly visits.

Criteria:

To qualify, patients must meet the following criteria:

  • Dogs must have cytologic or histologic diagnosis of multicentric lymphoma
  • Dogs must be > 10 kg body weight
  • No current treatment for cancer (including prednisone)
  • No current treatment with cyclosporine A or other drugs that affect the immune system
  • No current treatment with complementary or alternative medicines/supplements
  • No significant concurrent health issues

Client Savings:

Various diagnostic tests for clinical staging and up to 4 treatments of the new therapeutic will be provided as part of participation in the study.

Primary Study Contact:

Dr. Mike Lucroy (Medical Oncology and Director, Clinical Studies) at michael.lucroy@medvet.com or 317.872.8387.

Past Clinical Trials at MedVet Hospitals

The following trials are no longer accepting new patients:

  • Dogs with Dry Eye
  • Large Dogs Requiring Ruptured Cranial Cruciate Ligament Repair
  • Cats with Diabetes Mellitus
  • Small dogs requiring ruptured cranial cruciate ligament repair
  • Dogs with pruritus
  • Dogs with osteoarthritis
  • Large dogs requiring ruptured cranial cruciate ligament repair
  • Dogs with congestive heart failure (4 completed studies)
  • Dogs with t-cell lymphoma
  • Dogs with congestive heart failure (multi site study)
  • Dogs with mast cell tumors
  • Dogs with diabetes mellitus (2 completed studies)
  • Dogs with hip dysplasia
  • Dogs requiring cranial cruciate or luxating patella repair surgery (post-operative pain study)
  • Dogs with ruptured cranial cruciate ligaments
  • Dogs with melanoma, osteosarcoma, soft tissue sarcoma, and squamous cell carcinoma
  • Cats with congestive heart failure
  • Dogs with nasal carcinoma
  • Cats with oral squamous cell carcinoma
  • Dogs with atopic disease
  • Dogs with epilepsy
  • Dogs with lymphoma
  • Dogs with Glioma

Contact Us

If you have a pet that you believe may qualify for a clinical study, please contact your primary care veterinarian and they can work with us to determine if a clinical trial is the best option for your pet. If you are a veterinarian with a patient that you believe could benefit from a clinical study, please contact us.

MedVet Clinical Trials

(614) 310-1722

clinical.studies@medvetforpets.com

If you would like to learn more about MedVet’s Clinical Studies Center or how you can collaborate with one of the clinical investigative teams at MedVet, click here.