Antimicrobial Coverage for Severe Soft Tissue Infections in Dogs

Careful consideration should be made as to the antibiotic used in dogs with severe soft tissue infections with subcutaneous cellulitis, pyrexia, +/- signs of severe sepsis or septic shock.  Some dogs have a history of injury but others may not. Approximately 60% of these dogs have strep or staph as the causative agent.  Strep in particular is good at causing septic shock.  Fluroquinolones are contraindicated in severe soft tissue/necrotizing infections because they have limited activity against…

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Important: Other Sources of Xylitol to Dogs

Xylitol is a sugar-free sweetener used in chewing gum, baked goods, and many other products created for human consumption. It is commonly used by people with Diabetes Mellitus due to its low glycemic index and low-calorie content. Xylitol can be highly toxic to dogs, causing low blood sugar and liver failure.  The hypoglycemia is caused by insulin release stimulated by xylitol.  This effect generally lasts 12-24 hours but can be delayed.  The liver failure…

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Grape Juice – Is it Toxic?

We make dozens of calls to the poison control companies and we thought we would pass on this tip. We had a couple recent calls about dogs ingesting grape flavored products. What we learned was that most products processed with grapes are so dilute that they have never had a case that developed toxicity from this type of ingestion and therefore do not feel they are toxic.

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Toxic Dose of Naproxen in Dogs

Naproxen, most commonly known by the names Midol® and Aleve®, is a nonsteroidal anti-inflammatory drug (NSAID).  It works by reducing hormones that cause inflammation and pain. Like other NSAIDs, it can be used therapeutically in dogs but overdoses and toxicities are common. Naproxen has a narrow margin of safety. Unlike humans and many other species who eliminate naproxen in urine, dogs require extensive enterohepatic recirculation and eliminate naproxen in the feces. This accounts for a…

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Bromethalin Toxicity in Dogs and Cats

Rodenticides were once all anti-coagulant based. With the increased incidence of criminal use, and safety concerns for children and wildlife, most governments have been phasing out anti-coagulant formulas and turning to bromethalin-based poisons that cause intractable seizures. “We had anecdotes for anti-coagulants,” says Evans. “But regrettably they don’t exist for bromethalin, necessitating a multi-step deconamination protocol including inducing vomiting, promoting toxin absorption with activated char- coal, and very strict watch with supportive care.” She adds…

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